Major research emphases include signal transduction, biochemistry and pathobiology, gene regulation, cell systems biology, cell and tissue ultrastructure, membrane structure and function, molecular aspects of neurobiology and endocrinology, genetics and metabolism of microorganisms, virology and immunology and enzymology with an emphasis on protein dynamics and folding, as well as cytochrome P-450s.

Program faculty are drawn from several departments at Kent State University, University of Akron, Cleveland Clinic Foundation and Northeast Ohio Medical University (NEOMED). Additional participant faculty are located at area clinical facilities and hospitals. This multi-departmental and inter-institutional structure gives doctoral candidates access to the talents of a broadly diverse research faculty, as well as significant research facilities and resources.