?Using evolution as the unifying theme of biology, we emphasize current biological methods and rigorous conceptual analyses at all scales of organization, from molecules to cells to organisms to ecological communities. We encourage biology majors to interact extensively with professors and with each other, and we use a variety of learning activities to illustrate the tools of the trade, to reinforce concepts, and to apply problem-solving techniques. We prepare our students to think critically about important biological issues and to apply their informed analyses as citizens and professionals.