My brother did B.Tech and M.Tech in Biotechnology. According to him, it’s not a good idea to pursue Biotechnology in distance mode. Distance mode education works best for subjects that have less practical work. 

Biotechnology, on the other hand, requires extensive lab work and teacher-student interactions. Basically, Biotechnology is an interdisciplinary course. So, doing a regular degree or an engineering degree in Biotechnology will be far better.