NIPER JEE 2025 PATTERN & SYLLABUS

NATIONAL LEVEL ONLINE TEST

    NIPER JEE 2023 Exam Pattern, Marking Scheme, Syllabus, & Preparation

    NIPER JEE 2023 Exam Pattern will consist of 200 Multiple type questions and each question will carry one mark. There is a negative marking in the paper and 0.25 marks will be deducted for every incorrectly answered question. The exam will be conducted for a duration of  2 hours in online mode. National Institute of Pharmaceutical Education and Research conducts a Joint Entrance examination (NIPER JEE) every year for admission to M. Pharm, M.S.(Pharm.), M.Tech.(Pharm.), MBA (Pharm.) and Ph.D. courses (Pharmaceutical and Biological Sciences disciplines). NIPER JEE 2023 will be conducted on June 12, 2023. 

    • NIPER JEE 2023 Question paper will comprise questions that will be objective in nature and you need to select one out of the given 4 options.
    • The syllabus would consist of Chemistry, Biotechnology, Pharmacology, and Pharmaceutical subjects, the syllabus for which is given below. 
    • The medium of NIPER JEE 2023 is English.
    NIPER JEE 2023 Admit CardNIPER JEE 2023 EligibilityNIPER JEE 2023 Result

    Pattern Highlights

    NIPER JEE 2023 Exam Pattern Highlights

    • Exam Mode-  Online 
    • Number of papers- 1
    • Number of sections – 1
    • Question Paper Type – MCQ (Multiple Choice Questions)
    • Total Marks - 200 marks
    • Exam duration – 2 hours
    • Exam language – English

    Marking Scheme

    NIPER JEE 2023 Marking Scheme

    The marking scheme for NIPER JEE is very simple. The exam has 200 questions. NIPER JEE Marking Scheme 2023 is as follows.

    Marks Awarded for Right Answer+1 
    Marks Deducted for Incorrect Answer-0.25


    Syllabus 2020

    NIPER JEE 2023 Syllabus

    SubjectTopics
    Natural ProductsSecondary metabolites
    Phytochemistry
    Methods of extraction, isolation and characterization of natural products
    Biosynthetic pathways
    Important therapeutic classes
    Primary metabolites
    Marine natural products
    Plant growth regulators
    Spectroscopy
    Dietary antioxidants
    StereochemistryPharmacology and toxicology
    Evaluation of formulation, principles and methods of release control in oral formulations
    Bioavailability, bioequivalence studies
    Compartmental modeling
    Packaging
    Dosage forms
    Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities
    (TDDS)
    Fischer, sawhorse and newmon projection formulas
    Standardization of natural products
    Various adrenergic, cholinergic and other receptors
    Pharmaceutics and formulation (Pharmaceutical Technology)
    Pharmacokinetics
    Pharmacodynamics
    Pharmacological effect, desired, undesired, toxic, adverse effects
    Bioavailability, bioequivalence, various factors of ADME
    Drug metabolism
    Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways
    Pharmacological screening
    Mechanism of drug action
    Drug-receptor interaction
    Detailed study of CNS pharmacology Transdermal drug delivery systems
    Diseases
    Chemotherapy and pathophysiology
    Bioassay methods
    Drug delivery systems (DDS)
    Carriers in DDS
    Biological sources of important classes of natural products
    Parenteral
    Drug targeting
    Complexation
    Solubilization
    Dosage form development- stages, implications of dosage form
    Viscosity measurements
    Pharmaceutical analysisStability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability
    Various analytical techniques
    Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.
    Solubility
    Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS.
    Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc. 
    Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns
    Osmolality, osmolality, osmotic pressure, conductivity, Preservatives, Media for bioassay.
    Spectroscopic methods
    Electrophoresis
    UV-Visible
    NMR
    XRD
    IR
    Fluorimetry
    HPLC
    IR
    GC
    LCMS
    Mass
    NMR Peaks
    Particle sizing
    Chromatography- detailed QA and QC: GLP, TQM, ISO system
    Preformulation, cyclodextrin inclusion compounds
    Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.
    Dosage forms, Stages of dosage form development
    Biotechnology and biochemistryPharmaceutical technology
    Classification of enzymes and their functions mechanism of action of
    Genetic Engineering
    Blotting techniques(Western, southern)
    Gel electrophoresis
    Gene cloning
    Immunoassays, protein
    RNA synthesis
    DNA synthesis
    rDNA technology
    Gene expressionMutation
    Replication
    Transcription, translation
    Recombination, bacteriophages
    CloningFermentation
    Methods, isolation of nucleic acids, enzymes in cloning
    ChemistryBasic organic chemistry and biochemistry Stereochemistry
    Osazone test
    Mutarotation
    Medicinal chemistry and Bulk Drugs
    Keto-enol tautomerism
    IUPAC nomenclature
    Introduction to thermal methods of analysis
    Introduction to Redox reactions
    Imine-enamine
    Hybridization
    Amino acids proteins
    type of stereoisomer
    Basic methods of synthesis of various organic compounds
    Named reactions
    Various Heterocycles, Heterocycle synthesis, reactions
    Tautomerism
    Spectroscopy
    Resolution methods
    Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
    Racemic mixture
    R and S nomenclature
    Reactions like Cannizarro’s reaction
    Pericyclic reactions
    Ester hydrolysis
    Huckel’s rule reaction mechanisms-
    E and Z isomerism
    Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen
    Chromatography
    Carbohydrates classification
    Aromaticity
    AptitudeSimple Mathematics
    logical reasoning and data analysis,
    questions based on English language 
    PharmacologyBioavailability, bioequivalence, various factors of ADME
    Bioassay methods, various requirements. Brief knowledge of the statistical tests.
    Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases.
    Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion.
    Study of basis of threshold areas of work in NIPER in pharmacology dept. Mentioned in brochure.
    Detailed study of CNS pharmacology specially opiod receptors
    Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects.
    Drug metabolism: various pathways and other details.
    Drug interactions, agonist, antagonist, Mechanism of drug action, drug-receptor interaction.
    Various adrenergic, cholinergic and other receptors
    partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc.
    PhytochemistryMethods of extraction, isolation and characterization of natural products.
    Various separation techniques used for isolation of natural products.
    Biosynthetic pathways.
    Primary metabolites, their examples
    Secondary metabolites, various classes of secondary metabolites (eg. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, etc.).
    Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynaecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc.
    Dietary antioxidants, Marine natural products, Plant growth regulators.
    Fischer projection formulas.
    Biological sources of important classes of natural products. (Selected ones only)
    Standardization of natural products, analytical pharmacognosy.
    What is difference between natural products and pharmacognosy ?
    Some knowledge about types and preparation of ayurvedic formulatios like asava, arista etc.

    Recommended Books

    NIPER JEE 2023 Recommended Books

    NIPPER JEE
    BookAuthorSubject
    Advanced Organic chemistryBahl and Bahlreactions, various methods of synthesis of organic compounds
    Organic chemistryMorrison Boydreactions, various methods of synthesis of organic compounds
    PharmacologyRang and Dale  -
    BiochemistryU.Satyanarayana -
    BiotechnologyU.Satyanarayana -
    Elementary Organic SpectroscopyYR SharmaPrinciples and chemical applications
    Medicinal chemistryWilliams and LemkePharmacy
     Mass SpectroscopySilversteinPharmaceutical analysis
    Pharmaceutical BioassaysKastureBioassay and Screening
    Analytical chemistryGarry Christen ()Chemical Methods

    NIPER JEE Preparation Tips

    • Early Preparation: It is advised that candidates start their NIPER JEE preparation as early as possible to avoid last minute stress. Make a study plan and stick to the same.
    • Pattern and Syllabus: Before you start preparing for the exam, a thorough understanding of the pattern nd syllabus is of vital importance.
    • Study Plan: Creating a proper time table by allowing a particular amount of time to each topic helps to properly learn the subjects.
    • Revise: Daily practice and revision of the topics and formula already learnt helps candidates to prepare in an advanced way.
    • Be Healthy: For best preparation of any exam, it is vital to maintain a healthy lifestyle. Avoid staying up late, spending too much time on scree, and ensure a proper diet.

    Important Instructions

    NIPER JEE 2023 Important Instructions

    These are the following instructions you need to follow for NIPER JEE 2023

    • You should bring your own HB pencil
    • You should darken the circle properly in ORS sheet
    • Half or partially darkened circles will not be considered for evaluation
    • Write down your registration number clearly on the first sheet
    • No other stray marks should be made on the ORS sheets.
    • The duly filled application form needs to be sent to the institute.
    • Answers must be marked as per directions specified in the ORS sheet, question booklet and by the invigilators in the examination hall just before the commencement of examination.
    • The circles need to be darkened only using black ball pen.

    *The article might have information for the previous academic years, which will be updated soon subject to the notification issued by the University/College

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