Biomedical engineers apply the fundamentals of mathematics, physics, chemistry, and biology to solve medically relevant problems. Examples of biomedical engineering activities include medical device design, fabrication and testing, prosthesis fabrication, ergonomics and human factors, physiological function monitoring, home health care technology development, biomedical informatics, functional imaging and tomography, biomaterial development and biocompatibility, artificial tissue and organ fabrication, cell- and biomolecule-based sensors and therapeutics, gene therapy development, and biomedical microsystems.