The Department of Biochemistry and Molecular Biology (BMB) at the University of Miami is committed to maintaining our discipline as a central science and strives for excellence by sustaining the current areas of strength, fostering interdisciplinary and clinical translational research, and expanding the research portfolio to evolving areas of inquiry and discovery. Our expertise in RNA biology, understanding DNA stability and repair, studying the biophysical nature of biomolecules, and gaining insight into cellular signaling pathways has been recently expanded by the arrival of researchers specialized in the design of natural and semi-synthetic biomolecules, as well as molecular-based devices that can be employed in translational medicine and other bionanotechnology applications. The commitment of the Miller School to increase growth in the basic sciences will continue to provide our department with new and exciting opportunities to enhance our prominence in biomedical research.