The curriculum is an interdisciplinary program, and its faculty is drawn from various administrative units of the schools of medicine, pharmacy, and public health. The training faculty also includes scientists at government laboratories on campus or in the Research Triangle Park (e.g., EPA, NIEHS). The research interests of the faculty include most areas of toxicology, with particular emphasis on understanding the links between the environment and health risks, the mode of action of toxicants and disease pathogenesis, and how emerging knowledge could be translated into prevention strategies, new therapeutic interventions, and an improved scientific basis for risk assessment.The main areas of research concentration are molecular carcinogenesis, mechanistic toxicology, neurotoxicology, cardiopulmonary toxicology, hepatic toxicology, computational toxicology, developmental toxicology, immunotoxicology, drug and xenobiotic metabolism, and ethanol toxicology. Multidisciplinary efforts are directed at environmental toxicology, systems biology, animal models of human diseases, translational research, and biomarkers. The faculty generally does not conduct research in the areas of aquatic toxicology, forensic toxicology, the ecological aspects of toxicology, or studies in invertebrate systems. The research activities of the Curriculum in Toxicology are conducted in the laboratory facilities assigned to each faculty member by a participating administrative unit.