• A recent £2.5m University commitment to these Chinese collaborations has led to the appointment of four research fellows whose efforts are focused on developing research which has global impact.
  • In support of these activities, we now seek to employ a smart and motivated PhD student to work on this translational project by developing human glial models of neuropsychiatric disorders.
  • Neuropsychiatric disorders (NPDs) such as schizophrenia and mood disorders begin early in life, affect 1 in 17 people worldwide and have no effective treatments. Glial dysfunction plays a leading role in the pathogenesis of NPDs.
  • Modelling NPDs using patient-derived induced pluripotent stem cells (iPSCs) by subsequent differentiation into glial cells will provide a novel insight into altered glial dysfunction and help to develop novel therapeutic approaches.