Question:medium

Which of the following enzymes is directly inhibited by statins to reduce cholesterol biosynthesis in the liver?

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HMG-CoA reductase is the rate-limiting enzyme in the cholesterol synthesis pathway. Statins block this enzyme, reducing LDL levels significantly.
Updated On: Nov 26, 2025
  • Lipase
  • HMG-CoA reductase
  • Amylase
  • Pepsin