Question:medium
In the following reaction, the major product (H) is
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In the following reaction, the major product (H) is
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Using a simple frame or just bolding for the box
Key Points:
Grignard reagents (RMgX) add to ketones/aldehydes to form alkoxides.
Alkoxides are strong nucleophiles.
Intramolecular S$_N$2 reactions can occur if a nucleophile and a suitable leaving group are present in the same molecule, appropriately positioned (favored for 5/6-membered rings).
The sequence is: 1) Grignard addition, 2) Intramolecular cyclization.
Updated On: Nov 28, 2025
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