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In DNA replication, which enzyme is responsible for unwinding the double helix and separating the DNA strands?

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In DNA replication, remember that helicase "unzips" the DNA by breaking hydrogen bonds, while other enzymes like DNA polymerase and ligase build and join the new strands.
Updated On: Nov 26, 2025
  • DNA polymerase
  • Helicase
  • Ligase
  • Primase

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